Center for Addiction Medicine

Amy C. Janes, PhD

Amy Janes Headshot

Director of the Functional Integration of Addiction Research Laboratory at the McLean Imaging Center, and Assistant Professor of Psychiatry at Harvard Medical School

Contact:     (617) 855-3244



Dr. Janes conducts clinical neuroimaging studies of addictive disorders to define the neurological basis of risk for addictive disorders to inform efforts at personalized treatment. Her mentorship collaborations with junior faculty, postdoctoral fellows and graduate students have resulted in a number of publications, fellowship grant awards, and successful defense of thesis work. Dr. Janes is now supervising two pre- and two post-doctoral trainees in ongoing research funded through her independent NIDA R01 awards. She has co-authored eleven papers with Dr. Evins, most recently in 2017, and also published with Drs Rigotti, Fava, and Lukas.


Current Projects

Defining individual differences in tobacco smokers using multimodal neuroimaging

NIDA R01DA039125 2015- 20

Differences in brain reactivity to smoking cues predict relapse vulnerability and suggest the need for more personalized cessation treatment. Multi-modal neuro-imaging techniques will be used to comprehensively phenotype high and low cue-reactive smokers, which will be a first step toward the development of personalized smoking cessation therapy


Independent scientist career development award

NIDA K02 DA042987        2017- 22

This Award seeks 5 years of protected time to solidify and advance the PI’s independent laboratory, which focuses on defining individual risk factors for addictive disorders and their related neurobiological mechanisms. The K02 protected time will further this objective by allowing the PI to (1) acquire new skills in high-density electro-encephalography (EEG/ERP) in conjunction with advanced source localization techniques; (2) mentor junior scientists; and (3) extend her research portfolio through collaborations


Mechanisms of mindfulness of smoking cessation: optimizing quality and quantity

NCCAM R61 AT009337 2016-21

Recent work suggests that mindfulness training is an effective intervention for smoking, and may work by decoupling craving from smoking behavior. The proposed study will test the neural mechanisms of mobile mindfulness training delivered by smartphone.

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